multiply with the conjugate in numerator again and again you will get 

lim_x->∞ ((x+1)(x+2)(x+3)(x+4) - x⁴)/((x+1)(x+2)(x+3)(x+4))^1/4 + x )*((x+1)(x+2)(x+3)(x+4))^1/2 + x² )

after solving the numerator get a 3 power expression of x then take 3 power of x common, similarly take x and 2 power of x from the first and second denominator terms